Preheat your oven to 400°F (200°C). Line a baking sheet with parchment paper.
In a large mixing bowl, whisk together the flour, granulated sugar, baking powder, and salt.
Add the cold, cubed butter into the flour mixture. Use a pastry cutter or your fingers to mix until the mixture resembles coarse crumbs.
Stir in the dried cranberries and orange zest until evenly distributed.
In a separate bowl, whisk together the heavy cream, egg, and vanilla extract until well combined.
Pour the wet ingredients into the dry ingredients, and gently mix until just combined. Be careful not to overmix.
Turn the dough out onto a lightly floured surface. Gently knead it a couple of times until it comes together. Pat the dough into a circle about 1-inch thick.
Cut the dough into wedges or use a round biscuit cutter to form individual scones. Place them on the prepared baking sheet.
Sprinkle coarse sugar on top of each scone for a sweet, crunchy topping.
Bake in the preheated oven for 15-20 minutes or until the scones are golden brown.
Allow the scones to cool on a wire rack for a few minutes before serving.
Notes
Serve warm with a pat of butter and additional orange zest for garnish.